2018 Application Information: Mentored Research and Career Development (KL2) Program


Joint Mentored Research Career Development (KL2/RL5) Program In Clinical and Translational Science and Gerontology




  1. Candidates for the KL2/RL5 Scholar program are early career faculty (Instructor or Assistant Professor) who have a professional doctoral degree or are completing postdoctoral training with an impending academic appointment. KL2/RL5 Scholars will be recruited from a wide range of health professions and related fields, including all specialties of medicine and surgery, nursing, psychology and other behavioral sciences, dentistry, pharmacy, pharmacology, epidemiology, biostatistics, allied health sciences, health services research, biomedical engineering and other postdoctoral professions. All applicants must have evidence of strong academic achievement and scholarship, as well as personal attributes such as high motivation and integrity.
  2. Applicants must be US citizens or non-citizen nationals, or must have been lawfully admitted for permanent residence and possess an Alien Registration Receipt Card (I-151 or I-155) or some other verification of legal admission as a permanent resident. Applications will be accepted from persons whose residence application is pending, but the residency status must be completed to receive a KL2/RL5 award. Individuals on temporary or student visas are not eligible.
  3. Applicants must be able to commit at least 75 percent of full-time professional effort to this Career Development Program and its related clinical/translational science research activities (50% effort may be permitted for surgeons).
  4. Applicants who are dually employed by the Health Science Center and the Veterans Administration may be restricted from the KL2/RL5 Scholar award, depending upon the extent of commitment (percent effort) to the VA. Federal salaries cannot be considered part of the required 75% KL2/RL5 institutional commitment.
  5. Applicants must not be, or have been, a Principal Investigator on a R01 or R21 award or a Project Leader on a subproject of a Program Project (P01), Center (P50, P60, U54) or other equivalent research grant award, or a Principal Investigator of a mentored research career development (K-series) grant. Applicants may have received prior support on an Institutional or Individual NRSA grant (F or T) or NIH small grant (R03).
  6. Please note that NIH rules preclude individuals funded by the KL2 program from receiving additional federal funds for the portion of effort not covered by the KL2  program. 
  7. RL5 participants may receive salary support from other federal sources consistent with the institution's salary scale as long as those sources do not specifically prohibit such salary supplementation. Nevertheless, individuals supported by NIH training and career development mechanisms (K, T, or F awards) may not receive salary or stipend supplementation from the RL5 program.


Recruitment and application processes will be coordinated through the IIMS Office of Research, Education, and Mentoring (OREM) Program and the Older American Independence Center (OAIC):

KL2 Program Directors:

Joel Tsevat, MD,       (tsevat@uthscsa.edu)
Don Dougherty, PhD (doughertyd@uthscsa.edu)

OAIC (RL5) Program Directors

Alfred Fisher, MD fishera2@uthscsa.edu                                                                                                                           Peter Hornsby, PhD hornsby@uthscsa.edu

KL2 OREM Program Support:

Kathlynn Wray (wrayk@uthscsa.edu)                                                                                                                           Phone: 567-4330

 OAIC RL5 Program Support:

Renee Hill hillR4@uthscsa.edu                                                                                                                                       Phone: 562-4100

APPLICATION TIMELINE: Applications for upcoming KL2/RL5 Scholar positions awaitng FED budget.   Application reviews and interviews will be completed by early TBD, and awards will be issued on TBD or as funding becomes available.


APPLICATION SUBMISSION: Applications should be submitted by email to KL2 Program Support (see above) as a single PDF document in the order listed under "Application Requirements" below, with the exception of letters of recommendation. Letters of recommendation must be on letterhead, with signature, and may be delivered in hard copy in sealed envelopes or by email from the recommender.  Letters of recommendation will not be accepted from the applicant's email.  Mentor biosketches, other support form, and trainee tables should be submitted electronically as part of the PDF document.


  • Review the Program Description and Frequently Asked Questions (FAQ) before preparing a KL2 application.
  • Complete the Application Face Page completely.
  • Proofread your application thoroughly for accuracy and completeness.
  • Apply as early as possible, and encourage persons providing letters of recommendation to submit their letters promptly.
  • The deadline for receipt of applications and letters of recommendation is November 21, 2016. Selection of KL2/RL5 Scholars will be announced on or before May1, 2017. Funding will start on May 1, 2017, or as funding becomes available.

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  • Face Page. Information on applicant’s name, school/department, contact information, mentor contact information, citizenship status, and research area of interest.
  • Abstract. A summary of the proposed career development activities including the applicant’s well articulated career goals and research interests and plans.
  • Applicant’s PHS Form 398 Biosketch (Use New Format) and Other Support Form.
  • Narrative. Up to 10 pages total; 11 point Arial font. Summarize your career goals, career development plan, reasons for applying to the KL2 Program, and proposed research. Three sections should include:
    • Candidate. Describe your commitment to a career in clinical and/or translational research, and how and why a multidisciplinary training program is important for your future research career. This section should address:
      • The applicant's background as well as interest in and commitment to a clinical/translational science career.
      • The applicant's potential to develop into a successful independent investigator as evidenced by research training/experience, scholarships, publications and presentations, and grant awards. (Separately, sealed letters of recommendation submitted with the application should compliment this section.)
      • The basis for selection of the Mentor.
      • Willingness to commit to at least 75% professional effort towards the objectives of the KL2 Program; a description of residual professional efforts should also be included
      • Plans to develop and submit an extramural application for career development or other research support while in the KL2 Program
    • Career Development Plan. Describe objectives of your immediate research interests/goals and how and why the KL2 Program is important to and will help achieve these objectives as well as future research career success. This section may include planned participation in lab meetings or journal clubs; attendance at research conferences; formal coursework on clinical and translational science topics; participation in additional training experiences in clinical or basic science; or informal educational activities such as short courses or workshops. Also, include a timeline of plans for the development and submission of an extramural application for continued career development or other research support.
    • Research Plan. Describe the proposed clinical/translational research project/plan. The Research plan must include separate sections on:
      • Specific Aims (one page)
      • Research Strategy
        • Significance
        • Innovation
        • Approach (including Hypotheses, Rationale, Preliminary Studies, Approach, Methods, and Analyses)
      • Cited literature (this will not be included in the page limitation)
  • List of Persons who will Provide LettersList all persons who will submit a letter of support for your application.  The list should include the names of the three people providing letters of recommendation, but it may also include the names of people who will provide letters as collaborators, consultants, or other roles that will support your proposed research project.
  • Letters of Recommendation:
    • A sealed letter of recommendation from the Research Mentor(s) addressing:
      • the applicant’s:
        • potential for a career in multidisciplinary clinical and/or translational research
        • potential as a future independent investigator
        • capability in pursuing the chosen research topic
        • career development plan towards the applicant’s career goals/objectives
      • the Mentor’s:
        • willingness to serve as the applicant’s mentor in research and career development
        • qualifications in the proposed research area
        • previous experience as a research supervisor, including a description of the nature and extent of supervision experience with professional post-doctoral trainees or junior faculty
    • Supporting information from the Mentor(s) must include:
      • PHS Form 398 Biosketch (Use New Format)
      • PHS Form 398 Other Support form
      • PHS Data Table 5A – Predoctoral Trainees of Participating Faculty Members
      • PHS Data Table 5B – Postdoctoral Trainees of Participating Faculty Members
    • PHS 398 forms can be found at NIH PHS 398 Forms.
    • PHS Data Tables for Trainees of Participating Faculty Members can be found at http://grants2.nih.gov/grants/funding/424/index.htm
    • Two additional sealed letters of recommendation addressing, at a minimum, the relationship to the applicant (the position on which they base their knowledge of the applicant), and the applicant’s background and potential for a career as an independent research investigator in clinical and/or translational science. At least one of these letters must be from a UT Health Science Center at San Antonio faculty member.

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  • The KL2/OAIC Program Directors or designee will review applications for completeness.
  • Qualified applicants will be selected on the basis of:
  • Evidence that the KL2/RL5 program will facilitate the applicant’s long-term research and career development goals in clinical and translational science
  • Prior research training and demonstrated performance
  • The Research Mentor
  • Recommendations from the Research Mentor and two independent references
  • The scope and focus of the research and career development/educational plan provided in the application. Specifically, how well will the KL2/RL5 program activities help achieve the applicant’s well articulated learning objectives?
  • The KL2/RL5 Review Committee will evaluate applications for scientific and technical merit. All applications will be scored on the 1-9 scale used by the NIH Center for Scientific Review. The following factors will be considered during the review:
  • Quality of the Applicant
    • Quality of applicant's academic, research, and publication/presentation record
    • Potential to become a successful investigator in multidisciplinary clinical/translational research
    • Commitment to a career in translational science
    • Potential to benefit from a multidisciplinary mentored research training program
  • Quality of Career Plans
    • Consistency of applicant's career goals with prior and current research experience
    • Likelihood that career plans contribute substantially to the applicant’s scientific and leadership development and necessary skill acquisition to conduct multidisciplinary clinical/translational investigations
  • Quality of Proposed Research
    • Scientific and technical merit of the research question, experimental design and methodology
    • Relevance of proposed research to the applicant's career objectives
    • Appropriateness of research plan to the stage of research development and as a vehicle for developing the research skills as described in the career development plan


  • KL2/RL5 Scholars will be selected after consideration of the following factors:
  • Quality and appropriateness of the applicant for this program
  • Quality and appropriateness of the career development plans
  • Quality of the proposed research
  • Overall diversity represented in the final scholar group
  • If an application is reviewed favorably, final acceptance into the Program will be contingent on receipt of a letter from the director/chairperson of the sponsoring unit documenting a commitment to providing sufficient time to meet the minimum 75% effort requirement of this award and addressing the prospects for the candidate’s appointment to a research or faculty position at the conclusion of the KL2/RL5 program. Failure to successfully address these issues may jeopardize final acceptance of the applicant into the KL2/RL5 program.

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