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Previous Translational Technology Supplement Awards

Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for 2015 – 2016.

Name Department Project Title
Michael Berton, MD, PhD


Novel regulation of inflammation in non-hematopoietic cells by the TLR adaptor TRAM
Paul Fitzpatrick, PhD Biochemistry
Molecular Basis of Phenylketonuria
Brian Hermann, PhD Biology
Single-cell gene expression studies to identify the human spermatogonial stem cell
Amrita Kamat, PhD Barshop Ctr
Beta2-adrenergic receptor activation and lipid metabolism
Rong Li, PhD Molecular Medicine
A Molecular Toggle with Dual Functionality for ERβ
Shamim Mustafa, PhD Pediatrics - Neonatology
Effect of mechanical ventilation on endogenous fetal lung mesenchymal stromal cells
Susannah Nicholson, MD Surgery
Trauma, Inflammation, and Injury to the Gastrointestinal Microbiome
Denise O'Keefe, PhD Medicine/Urology
The Role of Nuclear Fatty Acid Synthase in Aggressive Prostate Cancer
Matthew Reilly, PhD Biomedical Engineering
Torsional Indirect Traumatic Optic Neuropathy
Rene Renteria, PhD Opthamology
Assessing Neuronal and Vascular Dysfunction in Diabetic Retinopathy
Yuzuru Shiio, MD, PhD Greehey CCRI
Proteomic analysis of cytokine signaling in Ewing sarcoma
Luzhe Sun, PhD C&S Biology
High Throughput Screening for GLI3 Processing Activator for Blocking Castration Resistant Prostate Cancer
Guangming Zhong, PhD Microbiology
Gut microbiome on chlamydial pathogenicity in the upper genital tract


Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for 2012 – 2013.

Name Department Project Title
Yidong Bai, PhD Cellular & Structural Biology Metabolic Implications of mtDNA Mutations for Breast Cancer
Molly Bergman, PhD Microbiology & Immunology Crystal Structure of Yersinia pseudotuberculosis serine/theonine acetyltransferase YopJ
Bandana Chatterjee, Phd Molecular Medicine Coregulator Interaction with Methylated Androgen Receptor and its Implication in Prostate Cancer
Yong-Hee Patricia Chun, DDS, MS, PhD Periodontics Endocytosis of Dental Enamel Proteins
Nitin A Das, MD Cardiothoracic Surgery Cytokine Profile of Ischemia Reperfusion Injury in a Rat Lung Transplant Model after Inhaled Nanoparticle Tacrolimus
Tim Q Duong, PhD Research Imaging Institute Non-Invasive MRI of Quantitative Vitreous Oxygenation in Diabetic Retinopathy
E Paul Hasty, DVM Molecular Medicin Effect of Rapamycin on a Mouse Model for Human Cancer
Brian Peter Hermann Biology (UTSA) Human Spermatogonial Stem Cell Enrichment by FACS
Roman V Kuranov, PhD Ophthalmology Verification of MRI Identified Retinas Layers in Rats Using Optical Coherence Tomography
Octavian V Lie, MD, PhD Neurology Spatial Analysis of Interictal Epileptiform Discharges during the Sleep-wake Cycle in Medically Intractable Focal Epilpsy
Senlin Li, MD Medicine Macrophage-mediated Gene Delivery of Neurotrophic Factors for Parkinson's Disease
Carolina Livi, PhD Molecular Medicine Prevention and Treatment of Gastrointestinal Cancer by a New Rapamycin Enteric Formulation (eRapa)
James Mubiru, DVM, PhD Primate Center (TBRI) MicroRNA Expression in Plasma and the Prostate in Cynomolgus Monkeys with the Metabolic Syndrome
Nicolas Musi, MD Medicine-Center for Healthy Aging Effect of Aging and Exercise on Toll Like Receptor Expression and Signaling in Human Subjects
Luiz O Penalva, PhD, MS Cellular & Structural Biology RIPSeq Analysis Method for miRNA Target Identification
Xomalin Peralta, PhD Physics & Astronomy (UTSA) Internalization of Gold Nanoparticles by Neuronal Cells for Photo-thermal Ablation Applications
MD Mizanur Rahman, PhD Medicine Prevention of Age-associated Musculoskeletal Loss by n-3 Fatty Acids
Z Dave Sharp, PhD Molecular Medicine Gene Expression Effects of Rapamycin on Intestine and Colon
Gail E Tomlinson, MD, PhD Pediatrics/GCCRI Characterization of a Family Recurring Translocations in Hepatoblastoma
Degeng Wang, PhD Epidemiology and Biostatistics Utilizing GRO-seq to Improve Cancer Genomics
Lora Talley Watts, PhD Research Imaging Institute MRI evaluation of neuroprotective effects following purinergic receptor stimulation in a rat model of stroke


Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for June 2011 - April 2012

Name Department Project Title
Ricardo Aguiar, MD, PhD Medicine/Hematology & Medical Oncology Role of microRNA-155 in the regulation of CDK inhibitors in mature B lymphocytes
Bandana Chatterjee, PhD Molecular Medicine Androgen Receptor Methylation in Prostate Cancer Progression and Growth Inhibition of Prostate Tumor by the Synergistic Interplay between a RNA Virus and Rapamycin
Xiao-Dong Chen, MD, PhD Comprehensive Dentistry Rescuing of Aged Mesenchymal Stem Cells by Exposure to a Young Extracellular Matrix
Jannine Cody, PhD Pediatrics The Role of Myelin Cognition
Tyler Curiel, MD, MPH Medicine/CTRC Effects of chronic, oral rapamycin on regulatory T cell function
Lily Dong, PhD Cellular & Structural Biology Adiponectin signaling and regulation
Timothy Duong, PhD Research Imaging Institute High-resolution MRI of human retinitis pigmentosa
Sai Kam Hui, PhD Research Imaging Institute Improving ischemic stroke staging using diffusion kurtosis imaging
Scott Johnson, MD Cardiothoracic Surgery Evaluation of Inhaled Nanoparticle Tacrolimus in Attenuation of Ischemia Reperfusion Injury in a Rat Lung Transplant model
James Lechleiter, PhD Cellular & Structural Biology Regulation of Mitochondrial Fatty Acid Oxidation by Thyroid Hormone Receptors
Guang Li, MS Research Imaging Institute Longitudunal fMRI of visual responses in the retina in progressive retinal degeneration
Rong Li, PhD Molecular Medicine Identifying Molecular Distinction between Normal and Cancer Stem Cells
Hanyu Liang, PhD Medicine/Diabetes Role of TLR4 in lipid-induced inflammation and insulin resistance
Ai-Ling Lin, PhD Research Imaging Institute Neuroimaging Assessment of a Novel Strategy for Neuroprotection in Stroke
David Melton, BS Surgery MicroRNA Expression Patterns in Cytokine-Polarized Bone Marrow-Derived Macrophages
Martin Schwacha, PhD Surgery The Th-17 Response and Pulmonary Complications in the ICU
Mark Shapiro, PhD Physiology Role of neuronal “M-type” potassium channels as a neuroprotective mechanism during cerebrovascular stroke
Qiang Shen, PhD Research Imaging Institute Multimodal MRI of ischemic stroke in diabetic rats
Jane Shen-Gunther, MD Dept of Clinical Investigation (BAMC) Genotyping Human Papillomaviruses: Development and Evaluation of a Comprehensive DNA Microarray
Yen-Yu Shih, PhD Research Imaging Institute Ultra high resolution functional MRI of the rat cortex
LuZhe Sun, PhD Cellular & Structural Biology MRI for Evaluation of Brain metastasis of Breast Cancer
Bin Zhang, MD, PhD Medicine/CTRC Detection of antitumor T cell homing to tumors using MRI


Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for May 2010 - April 2011

Name Department Project Title
Abdul-Ghani, Muhammad A MD, PhD Medicine/Diabetes fMRI study of hypothalamus: implication to diabetes and obesity
Chatterjee, Bandana PhD Molecular Medicine The Role of SLAIN1 in prostate tumor development
Dahia, Patricia MD, PhD Medicine/Hematology & Medical Oncology Role of a novel transmembrane protein in endosomal signaling
Duong, Timothy PhD Research Imaging Institute High-resolution 31P Imaging and application to Acute Stroke at 11.7T
Karkar, Kameel Michel MD Neurology In Vivo Monitoring of Post-Stroke Epileptogenesis in Humans
Lee, Kihak PhD Research Imaging Institute Validation of a catheterized β+-probe for quantitative 18F-FDG PET studies in Alzheimer’s disease
Orihuela, Carlos, PhD Microbiology & Immunology Crystal Structure of Streptococcus pneumoniae PsrP BR domain
Osmulski, Pawel PhD, MSc Molecular Medicine NMR based determination of molecular mechanism of anticancer allosteric inhibitors of proteasome
Petacchi, Augusto PhD Research Imaging Institute An animal model for the study of cerebellar influence on the auditory system
Sharp, Zelton Dave PhD Molecular Medicine MRI imaging of neuroendocrine tumors in Rb+/- model of human cancers
Voruganti, V. Saroja PhD Genetics Effect of insulin on hypothalamic function measured with fMRI
Zhang, Bin MD, PhD Medicine The tumor-promoting role of CD73 in ovarian cancer

Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for October 2009 - April 2010

Name Department Project Title
Bandana Chatterjee, MSc, PhD Molecular Medicine The Role of MicroRNA-454 and its target stem cell gene in Prostate Cancer
Thomas Boyer, PhD Molecular Medicine Molecular basis of syndromic X-linked mental retardation
Timothy Duong, PhD Research Imaging Institute Supplement PET imaging to non-human primate stroke study
Ibtissam Echchgadda, MS, PhD Molecular Medicine Oncolytic activity of respiratory syncytial virus against prostate cancer
Amina El Jamali, PhD Medicine/Infectious Diseases Role of NOX in insulin resistance
Marc Feldman, MD Medicine/Cardiology Use of atomic absorbance spectroscopy to demonstrate nanocluster (nanorose) excretion in mice
Ana Garcia, PhD Molecular Medicine Study of ERα interaction with DNA using a biosensor cell line
Charles Keller, MD Cellular & Structural Biology Therapeutic Response of Rhabdomyosarcoma to IGFR kinase inhibitors
Addanki Pratap Kumar, Ph.D Urology Development of combination of prognostic markers for prostate cancer
Valerie Lee, DMD, PhD Restorative Dentistry Identification of microorganisms present in dental unit waterlines
Rong Li, BS PhD Molecular Medicine Adipose Stromal Cells (ASCS) and Breast Cancer R
Shalini Narayana, PhD Research Imaging Institute Expanding a Neural Model of Speech Using Virtual Lesions and Connectivity Studies
Qi Peng, PhD Radiology Layer-Specific Functional & Perfusion Imaging of Human Retina on 3.0 Tesla MRI
Rene Alan Santacruz, BA Medicine-Infectious Disease Hematopoietic Stem Cell Based Delivery of BDNF as a Novel Treatment for Alzheimer’s Disease
Monika Tokmina-Lukaszewska, PhD, MSc Molecular Medicine Probing molecular mechanism of proteasome-targeting drugs with mass spectrometry
Bin Zhang, MD, PhD Medicine The regulation of tumor-reactive T cell migration into tumor microenvironment by CD73


Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for June 2009-April 2010.

Name Department Project Title
Ricardo C Aguiar, MD, PhD Medicine/Hematology & Medical Oncology Therapeutic targeting of PDE4B and associated survival pathways in B-cell lymphomas
Michael Brumlik, Phd, MSc, BSc Medicine/Hematology & Medical Oncology A novel MAPK family in T. gondii
Tyler Curiel, MD, MPH Medicine/Hematology & Medical Oncology Novel clinical applications for interferon-α in cancer immunotherapy & Rational improvements in treatment for ovarian cancer
Kenneth Cusi, MD Medicine/Diabetes Early Screening and Intervention for Fatty Liver Disease (NAFLD) in Predominantly Hispanic Population with Type 2 Diabetes Mellitus (T2DM)
Patricia Dahia,  MD, PhD Medicine/Hematology & Medical Oncology Molecular Studies of a Novel Tumor Suppressor Gene
Benjamin Daniel, PhD Medicine/Hematology & Medical Oncology Differential gene analysis of natural Tregs versus cancer induced Tregs
Peter Dube, PhD Microbiology & Immunology New animal models for translational research in influenza and influenza associated sequelae
Lorena Havill, PhD Genetics The effects of hormone replacement on statistical shape and density modeling assessed bone strength
Karl Klose, PhD Biology Structure Determination of the Vibrio Cholerae virulence regulatory protein ToxT
Carolina Livi, PhD Epidemiology & Biostatistics Gene expression profiling of non-functional Tregs from naïve young adult B7-H1 female mice
Jane Lynch, MD/ Carisse Mendoza-Orsi, MD Pediatric Endocrinology & Diabetes Vitamin D in Youth with Non Alcoholic Fatty Liver Disease (NAFLD): A 24-week, observational study
Donald McEwen, BA, PhD GCCRI Comparison of the substrate specificity and apoptotic potential of mono- and di-phsphorylated JNK
Sue Stacy, PhD Cellular & Structural Biology Defining T regulatory cell phenotypes to be targeted for immune and autoimmune therapies
Christina Villar, PhD, DDS, MS Periodontics Regulation of oral epithelial cell endocytic and apoptotic pathways by Candida albicans

This is the first group of investigators to receive funding from the IIMS/CTSA Translational Technologies and Resources Supplemental Awards. The RFA was distributed in December 2008 and 20 applications were received by February 9, 2009. The primary specific aims of the Translational Technologies and Resources program are as follows:

  • Improve access to equipment and services necessary for innovative research.
  • Provide advice and consultation in the application of innovative technologies to translational research.
  • Provide an enhances and integrated educational program to support training in the use of advanced and evolving technologies in reasearch for students, fellows, researchers and their staff.

Current Translational Technology Supplement Awardees