Previous Translational Technology Supplement Awards
Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for 2015 – 2016.
| Name | Department | Project Title |
|---|---|---|
| Michael Berton, MD, PhD |
Microbiology |
Novel regulation of inflammation in non-hematopoietic cells by the TLR adaptor TRAM |
| Paul Fitzpatrick, PhD |
Biochemistry UTHSCSA |
Molecular Basis of Phenylketonuria |
| Brian Hermann, PhD |
Biology UTSA |
Single-cell gene expression studies to identify the human spermatogonial stem cell |
| Amrita Kamat, PhD |
Barshop Ctr UTHSCSA |
Beta2-adrenergic receptor activation and lipid metabolism |
| Rong Li, PhD |
Molecular Medicine UTHSCSA |
A Molecular Toggle with Dual Functionality for ERβ |
| Shamim Mustafa, PhD |
Pediatrics - Neonatology UTHSCSA |
Effect of mechanical ventilation on endogenous fetal lung mesenchymal stromal cells |
| Susannah Nicholson, MD |
Surgery UTHSCSA |
Trauma, Inflammation, and Injury to the Gastrointestinal Microbiome |
| Denise O'Keefe, PhD |
Medicine/Urology UTHSCSA |
The Role of Nuclear Fatty Acid Synthase in Aggressive Prostate Cancer |
| Matthew Reilly, PhD |
Biomedical Engineering UTSA |
Torsional Indirect Traumatic Optic Neuropathy |
| Rene Renteria, PhD |
Opthamology UTHSCSA |
Assessing Neuronal and Vascular Dysfunction in Diabetic Retinopathy |
| Yuzuru Shiio, MD, PhD |
Greehey CCRI UTHSCSA |
Proteomic analysis of cytokine signaling in Ewing sarcoma |
| Luzhe Sun, PhD |
C&S Biology UTHSCSA |
High Throughput Screening for GLI3 Processing Activator for Blocking Castration Resistant Prostate Cancer |
| Guangming Zhong, PhD |
Microbiology UTHSCSA |
Gut microbiome on chlamydial pathogenicity in the upper genital tract |
Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for 2012 – 2013.
| Name | Department | Project Title |
|---|---|---|
| Yidong Bai, PhD | Cellular & Structural Biology | Metabolic Implications of mtDNA Mutations for Breast Cancer |
| Molly Bergman, PhD | Microbiology & Immunology | Crystal Structure of Yersinia pseudotuberculosis serine/theonine acetyltransferase YopJ |
| Bandana Chatterjee, Phd | Molecular Medicine | Coregulator Interaction with Methylated Androgen Receptor and its Implication in Prostate Cancer |
| Yong-Hee Patricia Chun, DDS, MS, PhD | Periodontics | Endocytosis of Dental Enamel Proteins |
| Nitin A Das, MD | Cardiothoracic Surgery | Cytokine Profile of Ischemia Reperfusion Injury in a Rat Lung Transplant Model after Inhaled Nanoparticle Tacrolimus |
| Tim Q Duong, PhD | Research Imaging Institute | Non-Invasive MRI of Quantitative Vitreous Oxygenation in Diabetic Retinopathy |
| E Paul Hasty, DVM | Molecular Medicin | Effect of Rapamycin on a Mouse Model for Human Cancer |
| Brian Peter Hermann | Biology (UTSA) | Human Spermatogonial Stem Cell Enrichment by FACS |
| Roman V Kuranov, PhD | Ophthalmology | Verification of MRI Identified Retinas Layers in Rats Using Optical Coherence Tomography |
| Octavian V Lie, MD, PhD | Neurology | Spatial Analysis of Interictal Epileptiform Discharges during the Sleep-wake Cycle in Medically Intractable Focal Epilpsy |
| Senlin Li, MD | Medicine | Macrophage-mediated Gene Delivery of Neurotrophic Factors for Parkinson's Disease |
| Carolina Livi, PhD | Molecular Medicine | Prevention and Treatment of Gastrointestinal Cancer by a New Rapamycin Enteric Formulation (eRapa) |
| James Mubiru, DVM, PhD | Primate Center (TBRI) | MicroRNA Expression in Plasma and the Prostate in Cynomolgus Monkeys with the Metabolic Syndrome |
| Nicolas Musi, MD | Medicine-Center for Healthy Aging | Effect of Aging and Exercise on Toll Like Receptor Expression and Signaling in Human Subjects |
| Luiz O Penalva, PhD, MS | Cellular & Structural Biology | RIPSeq Analysis Method for miRNA Target Identification |
| Xomalin Peralta, PhD | Physics & Astronomy (UTSA) | Internalization of Gold Nanoparticles by Neuronal Cells for Photo-thermal Ablation Applications |
| MD Mizanur Rahman, PhD | Medicine | Prevention of Age-associated Musculoskeletal Loss by n-3 Fatty Acids |
| Z Dave Sharp, PhD | Molecular Medicine | Gene Expression Effects of Rapamycin on Intestine and Colon |
| Gail E Tomlinson, MD, PhD | Pediatrics/GCCRI | Characterization of a Family Recurring Translocations in Hepatoblastoma |
| Degeng Wang, PhD | Epidemiology and Biostatistics | Utilizing GRO-seq to Improve Cancer Genomics |
| Lora Talley Watts, PhD | Research Imaging Institute | MRI evaluation of neuroprotective effects following purinergic receptor stimulation in a rat model of stroke |
Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for June 2011 - April 2012
| Name | Department | Project Title |
|---|---|---|
| Ricardo Aguiar, MD, PhD | Medicine/Hematology & Medical Oncology | Role of microRNA-155 in the regulation of CDK inhibitors in mature B lymphocytes |
| Bandana Chatterjee, PhD | Molecular Medicine | Androgen Receptor Methylation in Prostate Cancer Progression and Growth Inhibition of Prostate Tumor by the Synergistic Interplay between a RNA Virus and Rapamycin |
| Xiao-Dong Chen, MD, PhD | Comprehensive Dentistry | Rescuing of Aged Mesenchymal Stem Cells by Exposure to a Young Extracellular Matrix |
| Jannine Cody, PhD | Pediatrics | The Role of Myelin Cognition |
| Tyler Curiel, MD, MPH | Medicine/CTRC | Effects of chronic, oral rapamycin on regulatory T cell function |
| Lily Dong, PhD | Cellular & Structural Biology | Adiponectin signaling and regulation |
| Timothy Duong, PhD | Research Imaging Institute | High-resolution MRI of human retinitis pigmentosa |
| Sai Kam Hui, PhD | Research Imaging Institute | Improving ischemic stroke staging using diffusion kurtosis imaging |
| Scott Johnson, MD | Cardiothoracic Surgery | Evaluation of Inhaled Nanoparticle Tacrolimus in Attenuation of Ischemia Reperfusion Injury in a Rat Lung Transplant model |
| James Lechleiter, PhD | Cellular & Structural Biology | Regulation of Mitochondrial Fatty Acid Oxidation by Thyroid Hormone Receptors |
| Guang Li, MS | Research Imaging Institute | Longitudunal fMRI of visual responses in the retina in progressive retinal degeneration |
| Rong Li, PhD | Molecular Medicine | Identifying Molecular Distinction between Normal and Cancer Stem Cells |
| Hanyu Liang, PhD | Medicine/Diabetes | Role of TLR4 in lipid-induced inflammation and insulin resistance |
| Ai-Ling Lin, PhD | Research Imaging Institute | Neuroimaging Assessment of a Novel Strategy for Neuroprotection in Stroke |
| David Melton, BS | Surgery | MicroRNA Expression Patterns in Cytokine-Polarized Bone Marrow-Derived Macrophages |
| Martin Schwacha, PhD | Surgery | The Th-17 Response and Pulmonary Complications in the ICU |
| Mark Shapiro, PhD | Physiology | Role of neuronal “M-type” potassium channels as a neuroprotective mechanism during cerebrovascular stroke |
| Qiang Shen, PhD | Research Imaging Institute | Multimodal MRI of ischemic stroke in diabetic rats |
| Jane Shen-Gunther, MD | Dept of Clinical Investigation (BAMC) | Genotyping Human Papillomaviruses: Development and Evaluation of a Comprehensive DNA Microarray |
| Yen-Yu Shih, PhD | Research Imaging Institute | Ultra high resolution functional MRI of the rat cortex |
| LuZhe Sun, PhD | Cellular & Structural Biology | MRI for Evaluation of Brain metastasis of Breast Cancer |
| Bin Zhang, MD, PhD | Medicine/CTRC | Detection of antitumor T cell homing to tumors using MRI |
Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for May 2010 - April 2011
| Name | Department | Project Title |
|---|---|---|
| Abdul-Ghani, Muhammad A MD, PhD | Medicine/Diabetes | fMRI study of hypothalamus: implication to diabetes and obesity |
| Chatterjee, Bandana PhD | Molecular Medicine | The Role of SLAIN1 in prostate tumor development |
| Dahia, Patricia MD, PhD | Medicine/Hematology & Medical Oncology | Role of a novel transmembrane protein in endosomal signaling |
| Duong, Timothy PhD | Research Imaging Institute | High-resolution 31P Imaging and application to Acute Stroke at 11.7T |
| Karkar, Kameel Michel MD | Neurology | In Vivo Monitoring of Post-Stroke Epileptogenesis in Humans |
| Lee, Kihak PhD | Research Imaging Institute | Validation of a catheterized β+-probe for quantitative 18F-FDG PET studies in Alzheimer’s disease |
| Orihuela, Carlos, PhD | Microbiology & Immunology | Crystal Structure of Streptococcus pneumoniae PsrP BR domain |
| Osmulski, Pawel PhD, MSc | Molecular Medicine | NMR based determination of molecular mechanism of anticancer allosteric inhibitors of proteasome |
| Petacchi, Augusto PhD | Research Imaging Institute | An animal model for the study of cerebellar influence on the auditory system |
| Sharp, Zelton Dave PhD | Molecular Medicine | MRI imaging of neuroendocrine tumors in Rb+/- model of human cancers |
| Voruganti, V. Saroja PhD | Genetics | Effect of insulin on hypothalamic function measured with fMRI |
| Zhang, Bin MD, PhD | Medicine | The tumor-promoting role of CD73 in ovarian cancer |
Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for October 2009 - April 2010
| Name | Department | Project Title |
|---|---|---|
| Bandana Chatterjee, MSc, PhD | Molecular Medicine | The Role of MicroRNA-454 and its target stem cell gene in Prostate Cancer |
| Thomas Boyer, PhD | Molecular Medicine | Molecular basis of syndromic X-linked mental retardation |
| Timothy Duong, PhD | Research Imaging Institute | Supplement PET imaging to non-human primate stroke study |
| Ibtissam Echchgadda, MS, PhD | Molecular Medicine | Oncolytic activity of respiratory syncytial virus against prostate cancer |
| Amina El Jamali, PhD | Medicine/Infectious Diseases | Role of NOX in insulin resistance |
| Marc Feldman, MD | Medicine/Cardiology | Use of atomic absorbance spectroscopy to demonstrate nanocluster (nanorose) excretion in mice |
| Ana Garcia, PhD | Molecular Medicine | Study of ERα interaction with DNA using a biosensor cell line |
| Charles Keller, MD | Cellular & Structural Biology | Therapeutic Response of Rhabdomyosarcoma to IGFR kinase inhibitors |
| Addanki Pratap Kumar, Ph.D | Urology | Development of combination of prognostic markers for prostate cancer |
| Valerie Lee, DMD, PhD | Restorative Dentistry | Identification of microorganisms present in dental unit waterlines |
| Rong Li, BS PhD | Molecular Medicine | Adipose Stromal Cells (ASCS) and Breast Cancer R |
| Shalini Narayana, PhD | Research Imaging Institute | Expanding a Neural Model of Speech Using Virtual Lesions and Connectivity Studies |
| Qi Peng, PhD | Radiology | Layer-Specific Functional & Perfusion Imaging of Human Retina on 3.0 Tesla MRI |
| Rene Alan Santacruz, BA | Medicine-Infectious Disease | Hematopoietic Stem Cell Based Delivery of BDNF as a Novel Treatment for Alzheimer’s Disease |
| Monika Tokmina-Lukaszewska, PhD, MSc | Molecular Medicine | Probing molecular mechanism of proteasome-targeting drugs with mass spectrometry |
| Bin Zhang, MD, PhD | Medicine | The regulation of tumor-reactive T cell migration into tumor microenvironment by CD73 |
Recipients of the Clinical and Translational Science Award (CTSA) Translational Technologies and Resources Supplemental Awards for June 2009-April 2010.
| Name | Department | Project Title |
|---|---|---|
| Ricardo C Aguiar, MD, PhD | Medicine/Hematology & Medical Oncology | Therapeutic targeting of PDE4B and associated survival pathways in B-cell lymphomas |
| Michael Brumlik, Phd, MSc, BSc | Medicine/Hematology & Medical Oncology | A novel MAPK family in T. gondii |
| Tyler Curiel, MD, MPH | Medicine/Hematology & Medical Oncology | Novel clinical applications for interferon-α in cancer immunotherapy & Rational improvements in treatment for ovarian cancer |
| Kenneth Cusi, MD | Medicine/Diabetes | Early Screening and Intervention for Fatty Liver Disease (NAFLD) in Predominantly Hispanic Population with Type 2 Diabetes Mellitus (T2DM) |
| Patricia Dahia, MD, PhD | Medicine/Hematology & Medical Oncology | Molecular Studies of a Novel Tumor Suppressor Gene |
| Benjamin Daniel, PhD | Medicine/Hematology & Medical Oncology | Differential gene analysis of natural Tregs versus cancer induced Tregs |
| Peter Dube, PhD | Microbiology & Immunology | New animal models for translational research in influenza and influenza associated sequelae |
| Lorena Havill, PhD | Genetics | The effects of hormone replacement on statistical shape and density modeling assessed bone strength |
| Karl Klose, PhD | Biology | Structure Determination of the Vibrio Cholerae virulence regulatory protein ToxT |
| Carolina Livi, PhD | Epidemiology & Biostatistics | Gene expression profiling of non-functional Tregs from naïve young adult B7-H1 female mice |
| Jane Lynch, MD/ Carisse Mendoza-Orsi, MD | Pediatric Endocrinology & Diabetes | Vitamin D in Youth with Non Alcoholic Fatty Liver Disease (NAFLD): A 24-week, observational study |
| Donald McEwen, BA, PhD | GCCRI | Comparison of the substrate specificity and apoptotic potential of mono- and di-phsphorylated JNK |
| Sue Stacy, PhD | Cellular & Structural Biology | Defining T regulatory cell phenotypes to be targeted for immune and autoimmune therapies |
| Christina Villar, PhD, DDS, MS | Periodontics | Regulation of oral epithelial cell endocytic and apoptotic pathways by Candida albicans |
This is the first group of investigators to receive funding from the IIMS/CTSA Translational Technologies and Resources Supplemental Awards. The RFA was distributed in December 2008 and 20 applications were received by February 9, 2009. The primary specific aims of the Translational Technologies and Resources program are as follows:
- Improve access to equipment and services necessary for innovative research.
- Provide advice and consultation in the application of innovative technologies to translational research.
- Provide an enhances and integrated educational program to support training in the use of advanced and evolving technologies in reasearch for students, fellows, researchers and their staff.
Current Translational Technology Supplement Awardees