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UT Health San Antonio Cancer Center Seeks LOIs for Clinical Translational Pilot Applications

Ut Health San Antonio Cancer Center logoThe UT Health San Antonio Cancer Center is soliciting applications to provide seed funding in the form of pilot grants in clinical translational projects. This is in anticipation of the potential release of a call for these projects from CPRIT. The goal is to assist investigators in gathering preliminary data for future grant applications. Projects must be translational in nature with the goal of leading to a better understanding of clinical efficacy or a therapeutic or device. Ideally, projects will propose innovative clinical studies that are hypothesis-driven and involve patients enrolled prospectively on a clinical trial or involve analyses of biospecimens from patient enrolled in a completed clinical trial where the outcomes are known. This will include but is not limited to:
  • Clinical studies of new/repurposed interventions including drugs, immunotherapy, radiation and surgical therapies, or therapeutic devices
  • Development and validation of biomarkers for predictive purposes associated with tumor response to treatment or those related to treatment
  • Pharmacogenomic studies aimed at identifying genomic profiles associated with increased/decreased efficacy or toxicity during clinical interventions.
  • Studies to discover/develop/validate predictive biomarkers using completed clinical trials (such as the list above). Outcomes for clinical trials could be response to therapy, side effects or efficacy in influencing the treatment target. The most attractive such study would include both: a clinical trial incorporating both an intervention and, potentially using novel clinical trial designs, development and/or validation of predictive biomarkers.

LOI due date: February 12

More details here...

Application here...