Mobile Logo in White

Evaluation and Implementation of a Nurse Driven Insulin Infusion Protocol for the Medical-Cardiac Intensive Care Patient

Principal Investigator: Maria C. Cerrato, RN, BSN
Co-Principal Investigators/Collaborators: Judy Juguilon, Darlene Deters
Organization: San Antonio Medical Center — North

Abstract

Problem

After 2 (two) random episodes of severe hypoglycemia (blood glucose (BG) < 40 mg/dl), on patient’s that were receiving continuous insulin infusions in the Intensive Care Unit; our facility decided to conduct further investigation to see if these results were truly random or if these episodes of hypoglycemia were more frequent than we believed.

Evidence

After the first month of data was collected, there was found an overall 21.5% compliancy with the current protocols. Of these results, 6.5% of hourly BG were not being performed. A total number of patients with BG 60-80 mg/dl was 7, BG 41-59 mg/dl was 3, and BG < 40mg/dl as 1 (one).

Strategy

The data we chose to collect was whether or not 1) the hourly BG was performed, 2) the current insulin protocols were being followed, and 3) to also monitor for any episodes of hypoglycemia, defined as BG < 60 mg/dl.

Practice Change

The decision was made to utilize the Atlanta Protocol for all continuous insulin infusions in the ICU. The Benchmarks established were missed hourly BG was to be < 2.5% and compliance with the protocol was 90% +/- 1.5 units/hr, with hypoglycemia being defined, for our facility, as BG < 80mg/dl and severe hypoglycemia (BG < 40 mg/dl) as not being acceptable.

Evaluation

Upon evaluation of this protocol it was found that our facility had a decrease of 5.1% in non-compliance with performing hourly blood glucose values, with a simultaneous decrease in hypoglycemia from 10 incidences with the previous protocol to no episodes of hypoglycemia.

Results

Compliance with the insulin protocol (+/- 1.5 units) increased from 21.5% to 97.4%. Rate of Hypoglycemia went to zero (0).

Recommendations

The findings we have at the current time are comparable to published results for other insulin protocol evaluations, and we continue to evaluate our current clinical practices in relationship to continuous insulin infusions.

Lessons Learned

Our previous insulin protocol was ineffective and difficult for nurses to use. It was evident that implementing a workable insulin protocol decreased our incidences of hypoglycemia and that our staff was much more compliant with monitoring blood glucoses; this improved patient care in the ICU.

Bibliography

  • Sung J, Bochicchio GV, Joshi M et al. Admission Hyperglycemia is Predictive of Outcomes in Critically Ill Trauma Patients. J TraumaM 2005; 59:80.
  • Krinsley JS, Association between Hypeglycemia and increased hospital mortality in a heterogenous population of critically ill patients. Mayo Clin Proc 2003; 78:1471.
  • Griesdale, DE, de Souza RJ, et al. Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE–SUGAR study data. CMAJ 2009; 180(8): 821.
  • Fahy BG, Sheehy AM, and Coursin DB. Glucose Control in the Intensive Care Unit. Crit Care Med 2009; 37(5):1769.
  • NICE–SUGAR study. Intensive versus Conventional Glucose Control in Critically Ill Patients. NEJM 2009; 360(13):1283.
  • Furnary AP, Wu YX, Bookin SO. Effect of hyperglycemia and continuous intravenous insulin infusions on outcomes of cardiac surgical procedures: the Portland Diabetic Project. Endocr Pract. 2004; 10(suppl 2):21. http://www.amarillomed.com/diabetes/hospform.htm. Accessed May 14,2009.
  • Inzucchi S. Management of Hyperglycemia in the Hospital Setting. NEJM 2006; 355:1903.
  • Hassan E. Hyperglycemia management in the hospital setting. Am J Health-Syst Pharm 2007; 64(Supp 6): S9.
  • Smith AB, Udekwu PO. Biswas S. et al. Implementation of a nurse-driven intensive insulin infusion protocol in a Surgical Intensive Care Unit. Am J Health-Syst Pharm 2007; 64:1529.
  • Rea RS, Donihi AC, Bobeck M et al. Implementing an Intranvenous insulin infusion protocol in the intensive care Unit. Am J Health-Syst Pharm 2007; 64:385.
  • Boord JB, Sharifi M, Greevy RA et al. Computer-based Insulin Infusion Protocol Improves Glycemic Control over Manual Control. JNL Am Med Informatics Assoc. 2007; 14(3): 277.
  • Wilson M, Weinreb J, and Soo Hoo GW. Intensive Insulin Therapy in Critical Care — a Review of 12 protocols. Diabetes Care 2007; 30(4): 1005.
  • Clayton SB, Mazur JE, Condren S et al. Evaluation of an Intensive Insulin Protocol for Septic Patients in a Medical Intensive Care Unit. Crit Care Med 2006; 34(12):2974.
  • Inzucchi SE and Siegel MD. Glucose Control in the ICU — How Tight is Too Tight? NEJM 2009; 360(13): 1346.
  • Davidson PC, Steed RD, Bode BS et al. Use of a Computerized Intravenous Insulin Algorithm within a Nurse-Directed Protocol for Patients Undergoing Cardiovascular Surgery. JNL Dia Sci Tech Symp 2008; 2(3):369.
  • Bode BS. Braithwaite SS. Steed RD. et al. Intravenous Insulin Infusion Therapy: Indications, Methods, and Transition to Subcutaneous Insulin Therapy. Endo Pract 2004; 10(Suppl 2):71.
  • Goldberg PA, Siegel MD, Sherwin RS et al. Implementation of a Safe and Effective Insulin Infusion Protocol in a Medical Intensive Care Unit. Diabet Car 2004; 27(2): 461.
  • Martin K and Hums W. Pharmacist Designed and Nursing-driven Insulin Infusion Protocol to Achieve and Maintain Glycemic Control in Critical Care Patients. JNL of Trau Nurs 2006; 13(3): 140.
  • Bode BS, Braithwaite SS, Steed RD et al. Intravenous Insulin Infusion Therapy: Indications, Methods, and Transition to Subcutaneous Insulin Therapy. Endocr Pract 2004; 10 (Suppl 2): 71.